Royal Air Force Typhoon jets have operated alongside French aircraft in a combined operation against an underground arms cache in Syrian territory operated by the IS group, as stated by the UK's MoD.
The facility, pinpointed through reconnaissance, was assessed as housing weapons and explosive materials, the statement said, and was positioned in hills just above the historic site of Palmyra in Syria's central region.
"The RAF jets employed Paveway IV guided bombs to hit a series of entry passages down to the depot... preliminary assessments suggest the target was engaged successfully," the MoD said.
There was no sign of any civilian impact in the operation late on Saturday and all the aircraft returned to base without incident, the MoD added.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as ISIS - imposed extremist governance over large swathes of both Syria and Iraq prior to its 2019 collapse.
"This operation demonstrates British leadership, and commitment to work closely with our partners, to eradicate any revival of Daesh and their harmful and extremist ideologies in the region," the British Defence Secretary the minister remarked.
UK warplanes have conducted patrols over Syria to "forestall any attempted resurgence" of IS after its defeat at the battle of Baghuz in the year 2019, the MoD reported.
"I extend gratitude to all the members of the UK armed forces participating in this operation for their skill and their valour," the Defence Secretary commented. "Including them were numerous UK service members stationed over Christmas and New Year. This mission, to take out dangerous terrorists who endanger our security, highlights how UK forces are prepared to act, continuously, protecting the UK within its borders and powerful internationally."
During December, the US military executed what it termed a "massive strike" targeting Islamic State objectives in Syria, after an attack resulted in the deaths of two American soldiers and a civilian linguist in the Palmyra area.
The UN estimates Daesh still boasts between 5,000 and 7,000 fighters in Iraq and Syria.